Cognitive & Mood
Selank
- Size
- 10mg
Specifications
Selank Technical Profile
OVERVIEW
What Is Selank Peptide?
Selank is a synthetic heptapeptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is based on the naturally occurring tetrapeptide tuftsin (Thr-Lys-Pro-Arg), which is a fragment of the immunoglobulin G heavy chain with known immunomodulatory properties. The selank peptide extends tuftsin's sequence with a Pro-Gly-Pro C-terminal addition, which enhances metabolic stability and adds novel biological properties to the parent compound.
Classified as a nootropic and anxiolytic research peptide, selank research has focused on its interactions with neurotransmitter systems, immune function pathways, and gene expression in the central nervous system. Selank nootropic research has demonstrated effects on GABA, serotonin, and dopamine systems in preclinical models, while selank anxiety research has documented behavioral effects in standard animal anxiety models. Researchers who buy selank online from VivePeptides receive a compound manufactured to selank 99% purity standards by a trusted USA supplier.
- 01
Nootropic Heptapeptide
Synthetic tuftsin analog with anxiolytic and immunomodulatory research properties
- 02
≥99% HPLC Purity
Every batch verified via high-performance liquid chromatography
- 03
USA Tested & Verified
Third-party analytical testing performed in USA laboratories
RESEARCH
Selank Mechanism of Action in Research
The selank mechanism of action involves complex interactions with multiple neurotransmitter systems and immune signaling pathways. Selank research has revealed that this peptide influences brain chemistry through several interconnected mechanisms.
GABAergic System Modulation
Selank research has demonstrated significant interactions with the GABAergic system, the primary inhibitory neurotransmitter network in the central nervous system. Studies indicate that selank may enhance GABA-mediated inhibitory neurotransmission by modulating GABA receptor sensitivity. Published research suggests selank influences the expression of GABA receptor subunit genes in specific brain regions, potentially underlying its observed anxiolytic-like effects in animal behavioral models (Seredenin & Gudasheva, CNS Neuroscience & Therapeutics, 2013).
Serotonergic and Monoamine Pathway Interactions
Selank anxiety research has documented the peptide's interactions with the serotonergic system. Studies in rodent models indicate that selank may influence serotonin metabolism and 5-HT receptor expression in brain regions associated with emotional regulation. Additionally, selank research has shown effects on dopamine and norepinephrine metabolism, suggesting a broad influence on monoamine neurotransmitter systems.
Immunomodulatory Pathways
Drawing from its tuftsin heritage, selank research has also explored immunomodulatory mechanisms. Studies indicate selank may influence the expression of interleukins and other cytokines, potentially modulating immune response patterns. This dual neuro-immune research profile distinguishes selank from many single-pathway nootropic peptides. ---
COMPARISON
Selank vs Semax: Research Peptide Comparison
Selank
Selank and semax are both Russian-developed synthetic peptides studied in nootropic and neuroscience research. While they share overlapping research contexts, they differ in origin, structure, and proposed primary mechanisms.
Semax
Both selank and semax are available from VivePeptides at ≥99% purity. Researchers studying anxiolytic mechanisms and neuro-immune interactions often choose selank, while those focused on BDNF expression and cognitive pathways may prefer semax.
| Feature | Selank | Semax |
|---|---|---|
| Origin | Tuftsin analog (IgG fragment-derived) | ACTH(4-10) analog |
| CAS Number | 129954-34-3 | 80714-61-0 |
| Amino Acids | 7 | 7 |
| Molecular Weight | 751.87 Da | 813.93 Da |
| Primary Research Focus | Anxiolytic and immunomodulatory research | Cognitive and neurotrophic research |
| Key Neurotransmitter Target | GABAergic system | BDNF/neurotrophic pathways |
| Immune Activity | Documented immunomodulatory effects | Limited immune research |
| Parent Peptide | Tuftsin (Thr-Lys-Pro-Arg) | ACTH(4-10) |
RESEARCH STUDIES
Selank Research Applications & Published Studies
Selank research spans two decades of published literature, with studies conducted primarily at Russian research institutions and expanding internationally.
Anxiolytic Research Models
Selank anxiety research includes numerous studies using established behavioral paradigms. Seredenin & Gudasheva (CNS Neuroscience & Therapeutics, 2013) reviewed selank's effects across multiple anxiety models, including the elevated plus maze and light-dark box tests in rodents. Published data indicate that selank produces measurable effects on anxiety-related behaviors in these standard preclinical models without the sedation commonly observed with GABAergic compounds.
Gene Expression and Neurotrophic Factor Studies
Selank research has included genomic studies examining its effects on gene expression in brain tissue. Published microarray data indicate that selank may modulate the expression of genes involved in neurotrophic signaling, synaptic plasticity, and inflammatory response. Studies have documented selank's influence on BDNF, NGF, and related gene expression in specific brain regions of rodent models.
Immunological Research
Building on tuftsin's known immunomodulatory properties, selank research has explored immune function effects. Published studies have documented selank's influence on cytokine expression patterns, including IL-6, IL-10, and TNF-α, in various experimental immune models. This immunomodulatory research profile makes selank unique among nootropic research peptides.
QUALITY ASSURANCE
Quality & Testing Standards
HPLC & Mass Spectrometry
Every selank batch undergoes HPLC and mass spectrometry analysis to verify peptide identity, sequence accuracy, and purity.
Third-Party Verified
All selank is independently tested at third-party USA-based analytical laboratories with complete documentation.
≥99% Purity Standard
VivePeptides selank consistently meets or exceeds ≥99% purity as verified by HPLC for reliable research results.
FAQ
Frequently Asked Questions About Selank
What is selank used for in research?
What purity is VivePeptides selank?
How should selank be stored?
What is the relationship between selank and tuftsin?
Is VivePeptides selank third-party tested?
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Selank
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